在3月，春暖花開的季(ji)節(jie)，讓(rang)我(wo)們熱烈恭賀中國農業大學的譚(tan)老師(shi)成功贏取了(le)恒遠(yuan)生物(wu)“SCI文獻獎學金”！譚(tan)老師(shi)之訂購了(le)恒遠(yuan)生物(wu)高敏ELISA試劑(ji)盒，使用了(le)我(wo)們的產品在《ADVANCED SCIENCE》雜志(zhi)上發(fa)表了文獻——Designing Self-Assembling Chimeric Peptide Nanoparticles with High Stability for Combating Piglet Bacterial Infections，IF影響因子高達16.8分！恒遠生物在此也非常感謝譚(tan)老師對我(wo)們信任與支持，希(xi)望通過(guo)我(wo)們的(de)不懈(xie)努力能(neng)為科研事業做出更大的(de)貢獻！讓我(wo)們再次祝賀譚(tan)老師！
Blood was collected from the orbital vein of the mice, ａnd using an enzyme-linked immunoassay to analyze cytokine levels in the serum. The inflammatory factor kit was purchased from Shanghai Hengyuan Biological Technology Co., Ltd.
Moreover, compared with the saline treatment group, the levels of pro-inflammatory factors TNF-α, interleukin-6 (IL-6), ａnd interleukin-1 (IL-1) in the serum of mice in the peptide nanoparticle treatment group were significantly reduced (Figure 6j–l). These cytokines are key factors affecting the inflammatory response in acute sepsis. Considering the action mechanism of peptide nanoparticles, combining them with LPS to reduce the circulation of endotoxins in vivo may limit the immunogenic potential of mice.[41] These results indicate that peptide nanoparticles not only exert direct antibacterial effects but also have immunomodulatory properties. These effects complement each other ａnd help prevent systemic bacterial infections. Hematoxylin ａnd eosin (H&E) staining showed pathological changes in the tissues of infected mice, including hepatocyte damage, vacuoles around the glomerulus, ａnd inflammatory cell infiltration (Figure 6i). After peptide nanoparticle treatment, tissue damage was largely prevented or restored
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